Best Weight Loss Supplements
There are several Weight Loss Supplements options available. This includes a wide range of pills, medications, and herbal supplements. These are stated to deal with weight loss, or at the very least make it easier to lose weight when used in conjunction with other techniques.
They usually operate by one or more of the following mechanisms:
- Reduce your appetite by making you feel fuller, allowing you to consume fewer calories.
- Reduce the absorption of nutrients like fat, resulting in fewer calories consumed.
- Increase your fat-burning ability.
Here are the science-backed reviews of the 08 most common weight loss pills and supplements.
1) Conjugated Linoleic Acid (CLA):
For years, CLA (conjugated linoleic acid) has been a common fat loss supplement. It is one of the “healthier” trans fats, which can be found in certain fatty animal foods such as cheese and butter.
Mode of action: CLA can help you lose weight by reducing your appetite, increasing your metabolism, and stimulating the breakdown of body fat.
Efficacy: CLA induced weight loss of around 0.2 pounds (0.1 kg) every week for up to 6 months in a large study of 18 separate studies. Another review study from 2012 found that when compared to a dummy pill, CLA will help you lose about 3 lbs (1.3 kg) of weight.
Side effect profile: CLA may have a variety of digestive side effects, and it can be dangerous in the long run, leading to fatty liver, insulin resistance, and inflammation.
Take-Home: CLA is an important weight-loss supplement, but it can have long-term negative consequences. The risk is not worth the small amount of weight loss.
2) Forskolin
Forskolin is a plant extract from the mint family that is said to help people lose weight.
Mode of action: It is thought to increase the levels of a compound called cAMP in cells, which could cause fat burning.
Efficacy: It decreased body fat and increased muscle mass while having no effect on body weight, according to a study of 30 overweight and obese men. Another study of 23 obese women showed no negative effects.
Side effect profile: There is also little information about the supplement’s protection or possibility of side effects.
Take-Home: The findings of two small studies on forskolin were contradictory. It’s best to stay away from this supplement until further testing has been completed.
3) Meratrim
Meratrim is a relatively new diet drug on the market. It’s a combination of two plant extracts that may alter fat cell metabolism.
Mode of action: It is claimed to make fat cells multiply more slowly, reduce the amount of fat they absorb from the bloodstream, and aid in the burning of stored fat.
Efficacy: Meratrim has only been the subject of one analysis so far. A total of 100 obese people were given either Meratrim or a dummy pill and were placed on a strict 2000-calorie diet. The Meratrim party had lost 11 pounds (5.2 kg) and 4.7 inches (11.9 cm) from their waistlines after 8 weeks. They have had a better quality of life, as well as lower blood pressure, cholesterol, and triglycerides.
Side effect profile: There have been no reports of side effects.
Take-Home: Meratrim induced weight loss and had a variety of other health benefits, according to one report. However, since the study was funded by the industry, further research is needed.
4) Glucomannan
The elephant yam, also known as konjac, contains glucomannan, a form of fiber.
Mode of action: Glucomannan absorbs water and transforms into a gel-like substance. It “sits” in your stomach and encourages satiety, allowing you to consume fewer calories.
Efficacy: Three human studies found that when glucomannan is paired with a balanced diet, it can help people lose 8-10 pounds (3.6-4.5 kg) in 5 weeks. Glucomannan is a fiber that feeds the good bacteria in the gut. It can also help with blood sugar, cholesterol, and triglycerides levels, as well as constipation.
Side effect profile: Side effects include bloating, flatulence, and soft stools, as well as the possibility of interfering with certain oral drugs if administered at the same time.
It’s necessary to take glucomannan with a glass of water about half an hour before meals.
Take-Home: When paired with a balanced diet, studies show that the fiber glucomannan can help people lose weight. It also improves a variety of health indicators.
5) Orlistat
Orlistat is a pharmaceutical product that is a listed over-the-counter drug. There are many brand names of Orlistat and one of the brand name is Xenical Alli.
Mode of action: This weight loss pill works by preventing a fat breakdown in the stomach, causing you to consume less calories from fat.
Efficacy: Orlistat can improve weight loss by 6 pounds (2.7 kg) as compared to a dummy pill, according to the review of 11 clinical studies. Orlistat has been shown in studies to lower blood pressure significantly and to minimize the risk of type 2 diabetes by 37%.
Side effect profile: This medication has a number of digestive side effects, including loose, oily stools, flatulence, and regular, difficult-to-control bowel movements, among others. It may also lead to a deficiency of fat-soluble vitamins including vitamins A, D, E, and K.
To reduce the risk of side effects, it is normally advised to eat a low-fat diet while taking orlistat. A low-carbohydrate diet (without drugs) has been shown to be just as successful as orlistat and a low-fat diet combined.
Take-Home: Orlistat, also known as Alli or Xenical, can help you lose weight by reducing the amount of fat you consume from your diet.
6) Hydroxycut
Hydroxycut has been around for over a decade and is now one of the most widely used weight loss supplements on the planet.
There are many varieties, but the most common is simply referred to as “Hydroxycut.”
Mode of action: Caffeine and a few plant extracts are among the ingredients that are stated to help with weight loss.
Efficacy: As per a study report, it resulted in a weight loss of 21 lbs. (9.5 kg) over a three-month span.
Side effect profile: You can experience anxiety, jitteriness, tremors, nausea, diarrhea, and irritability if you are caffeine sensitive.
Take-Home: Unfortunately, this supplement has only one analysis and no evidence of its long-term efficacy. More investigation is needed.
7) Garcinia Cambogia
Following its appearance on Dr. Oz’s show in 2012, garcinia cambogia became a global hit.
It’s a tiny green fruit with a pumpkin-like shape.
Hydroxycitric acid is contained in the fruit’s shell (HCA). This is the active ingredient in garcinia cambogia extract, a weight-loss supplement.
Mode of action: Animal experiments indicate that it can minimize cravings by inhibiting a fat-producing enzyme in the body and increasing serotonin levels.
Efficacy: Garcinia cambogia was compared to a dummy pill in a sample of 130 participants. There was no difference between the groups in terms of weight or body fat percentage. As per a review of 12 studies in 2011 on garcinia cambogia,it induced weight loss of around 2 pounds (0.88 kg) over several weeks on average.
Side effect profile: There have been no reports of severe side effects, but there have been several reports of minor digestive issues.
Take-Home: Despite the fact that garcinia cambogia may cause some weight loss, the effects are so minor that they are unlikely to be noticed.
8) Caffeine
Caffeine is the world’s most widely used psychoactive ingredients.
It’s naturally present in coffee, green tea, and dark chocolate, and it’s even applied to a lot of processed foods and drinks. Caffeine is a well-known metabolism booster that is often used in weight-loss supplements.
Mode of Action: Caffeine can improve metabolism by 3-11 percent and increase fat burning by up to 29 percent, according to short-term studies.
Efficacy: Caffeine’s effectiveness has also been shown in several studies to induce minor weight loss in humans.
Side effect profile: Excessive caffeine may cause anxiety, insomnia, jitteriness, irritability, nausea, diarrhea, and other symptoms in some people. Caffeine is also addictive and can interfere with sleep quality.
There’s no need to take a caffeine-containing supplement or tablet. Quality coffee and green tea are the best sources since they contain antioxidants and other health benefits.
Take-Home: In the short term, caffeine can increase metabolism and fat burning. Tolerance to the effects, on the other hand, can grow quickly.
Message to Recipients
These are the absolute winners, with the most facts to back them up, out of the 8 supplements:
For Weight Loss: Glucomannan, CLA, and Orlistat.
Increased fat oxidation: Green tea extract and caffeine.
Cutting carbs and increasing protein are also the most effective ways to lose weight, outperforming all diet pills combined.
We are expecting your share & comment.
Pharmacist. Nahid Chowdhury
B.Pharm (Bachelor In Pharmacy)
6 Years Experience In Industrial Pharmacy
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